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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
DEVELOPMENT AND INVESTIGATIONS ON HERBAL SYRUP
Author
Gadapuram Tharunkumar, C.R.Akila, Ramesh M, Vincent Vidyasagar Jenugu
Email
mail2tarunin@gmail.com
keyword
Syrups, Anticancer, Dextrose, Withania
Abstract
The rate of colon cancer incidence was low in India but is presently increasing; out of 3.5 million cancer cases, 35,000 suffer from colon cancer (Srikhande et al., 2007). The small growths (known as polyps) in colon are often benign, although some have the potential to develop and become cancerous. It is estimated that up to two thirds of colorectal polyps are pre-malignant and associated with a risk of colorectal cancer. Phytochemically the plant has been investigated for cardenolides, alkaloids, triterpenes and saponins and it is found to contain a variety of triterpenes and steroidal compounds and also to find out, a newer synthetic drug, for its anti-colon cancer potential and its toxic profile. In the current work, a syrup formulation with varying concentration of herbs in it and the same is tested for the anti-cancer activity. Two concentrations of the syrups were studied for the anticancer potential and its concluded to possess anti colorectal cancer activity. Before the clinical usage of extract, thorough toxicological profile has to be determined on the crude extracts as well as on isolated compounds to confirm the safety of the drug
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