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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
BIODEGRADABLE POLYMER MICRONEEDLES FOR CONTROLLED-RELEASE DRUG DELIVERY
Author
K. Shiva Kumar*, M.Purushothaman, H. Soujanya, S.Jagadeeshwari
Email
kothashivakumar21@gmail.com
keyword
Microneedles, TDDS, thermal polymers.
Abstract
Micro needles are used for NDDS(novel drug delivery system). Needles are one of the recent advances in drug delivery and have been proposed as a novel drug delivery system. The micro needles shape is designed for polymeric micro particles and this may overcome the injection & patches limits. Control release consists of both the functions of drug matrices and needles. These micro needles are strong and larger in size which is inserted in the skin to transfer the drug in order to stimulate nerve, but these needles may not touch deeper layer. When polymer needles are dissolved, it shows disposal of bio hazardous sharps waste after injecting the drug. In mild conditions of this study, the fabrication of micro needles are added with protein drug delivery to form mass production. This study observed that micro needles are inserting into the skin of the humans and doesn’t show any pain or sense. The low ratio &pyramides are used to dissolve micro needles when inserted in the skin to show adequate mechanical strength.
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