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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
STUDY OF ANTIFUNGAL DRUGS SUSCEPTIBILITY OF CANDIDA ISOLATES
Author
Lawhale MA, Goyal M, Sinha PK, Dhone PG, Shrikhande S, Murthy R, Rathod V
Email
pravin.dhone@yahoo.com
keyword
Candida, Antifungal therapy, Fluconazole, Voriconazole
Abstract
Fungal infections are a growing medical problem requiring prompt diagnosis with species identification and early adapted antifungal therapy. Among the increasing fungal infections, candida species are the most common in the recent few decades. Fluconazole, a triazole derivative has become the drug of choice for the treatment of candidiasis in immunocompromised patients. Antifungal susceptibility of candida isolates to fluconazole and voriconazole was performed by disc diffusion method. As many as 14.28% candida isolates showed resistance to fluconazole. Some of the non-albicans candida species like C. glabrata (40%) showed more resistance to fluconazole. Candida isolates showed 2.39% resistance to voriconazole
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