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American Journal of Oral Medicine and Radiology

Volume 5, Issue 2, 2018
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
A SAVOURY CASE REPORT OF DRUG INDUCED ERYTHEMA MULTIFORME: A RARE FORM
Author
Dr. Rakhi Chandak, Dr. Runal Bansod, Dr. Ramhari Sathawane, Dr. Ashish Lanjekar, Dr. Gunjan Moon
Email
runalbansod@gmail.com
keyword
Drug induced, Erythema multiforme, Steven-johnson syndrome.
Abstract
Erythema multiforme (EM), is an acute, mucocutaneous disorder, characterized by varying degrees of blistering and ulceration. It‟s a self-limited syndrome with distinctive skin lesions with or without mucosal lesions. The use of terminology "EM minor" and "EM major" is a reasonable approach to separating the classical mild cutaneous syndrome, as described by Hebra (EM minor), from the usually more severe syndrome, with marked mucosal damage, as described by Stevens and Johnson (EM major). The etiology of erythema multiforme is very complex. Its most likely a skin mediated immune reaction which occurs following exposure to a trigger in certain 'predisposed' individuals. The most common trigger factors are infection, in around 90% of cases, and medications in less than 10% of cases.2 The most commonly associated infection is herpes simplex virus (the cold sore virus). Drugs which have been identified as causative agents for EM include non-steroidal anti-inflammatory drugs (given for joint and muscle pain), antibiotics and anticonvulsants (used to treat epilepsy).This case report presents a case of a 27 years old male patient who developed erythema multiforme from ofloxacin and ornidazole and its successful management.
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