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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
EFFECT OF PALATABLE FOOD INGESTA ON FEEDING BEHAVIOR AND BLOOD GLUCOSE LEVEL IN RATS
Author
Manjula Suri1, Suneel Kumar, Suman Jain, Rashmi Mathur
Email
mnjlsuri@gmail.com
keyword
Diabesity, Non-nutritive sweeteners, Ingestive behavior, Palatability, Sucrose, Saccharin
Abstract
Diabesity has reached an epidemic proportion in India as well as worldwide. The use of non-nutritive sweeteners (NNSs) has been proposed to combat this menace. NNSs are calorie less healthy sugar substitutes while researchers suggest a contrary report of NNSs. Ingestive behavior plays an important role in diabesity development as it may provide excess calories. However, ingestive behavior is a complex process with a lack of experimental animal studies. Therefore, we studied ingestive patterns in the control, sucrose or saccharin (NNSs) fed rats along with a change in their body weight and blood sugar levels. The analysis allowed a comparison of ingestive behavior such as number of ingestive bouts, bouts licking rate, bouts duration as well as water and food intake patterns. Results show that control and sucrose-fed rats ingested 5 g food in the 2 h, and 4 h, respectively while saccharin fed rats have become “nibblers” during this period. Rats ingested sucrose in 6-bouts while saccharin in 4-bouts during the experiment. The study showed a temporal variation in sucrose versus saccharin induced ingestive behavior. The findings suggest that NNS's interferes with ingestive behavior which normally contributes to energy homeostasis and may induce metabolic derangements.
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