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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
EVALUATION OF CARDIOVASCULAR OUTCOME MANAGEMENT BY ANTI-HYPERTENSIVES
Author
Prasanthi B, Dasaradhi Ch, Revathi K, Kiranmai Y, Lavanya P
Email
santhi023@gmail.com
keyword
Hypertension, Therapeutic Approach, Therapeutic Outcome, Anti-Hyoertensives.
Abstract
The pathogenesis of essential hypertension is multifactorial and highly complex. Multiple factors modulate the blood pressure (BP) for adequate tissue perfusion and include humoral mediators, vascular reactivity, circulating blood volume, vascular caliber, blood viscosity, cardiac output, blood vessel elasticity, and neural stimulation. A possible pathogenesis of essential hypertension has been proposed in which multiple factors, including genetic predisposition, excess dietary salt intake, and adrenergic tone, may interact to produce hypertension. One mechanism of hypertension has been described as high-output hypertension. High output hypertension results from decreased peripheral vascular resistance and concomitant cardiac stimulation by adrenergic hyperactivity and altered calcium homeostasis. Hypertension is most prevalent in patients of age group 51-70 years. The BP and Echo (EDD, ESD, IVSD, PW, LA, and EF) results of the study concluded that the proper adherence and administration of antihypertensives is effective in normalizing the elevated BP levels and also reduced the risk of CV outcomes in most of the patients
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