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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
COMPARATIVE STUDY ON EFFICACY OF METFORMIN AND GLIBENCLAMIDE IN PATIENTS DIAGNOSED WITH TYPE-2 DIABETES
Author
Chokka Srilakshmi*, K. Siva Prasad, S.M. Imroz, B. Balasubramanyam
Email
chokkasrilakshmi1@gmail.com
keyword
NIDDM, Type-2 diabetes, Glibenclamide, Metformin, Fasting blood glucose.
Abstract
It was estimated that nearly 415 million people were diagnosed with diabetes mellitus, a common chronic disease in modern life in 2015. Only in India there were 69.2 million people diagnosed with diabetes in 2015, making India an epicenter for diabetes. It is calculated that an average of 123.5 million people may present with diabetes by 2040. The main aim of the study is to compare the safety and efficacy of metformin and Glibenclamide in people diagnosed with type-2 diabetes. To make it easier for the health care professionals in selecting an alternative or add-on drug for management of diabetes in patients. Institutional Ethics Committee (IEC) members have approved for the study to be carried out in the respective hospital. After approval for the study, it was carried out for a period of 6 months and the patients were asked to review at regular intervals. Patients newly diagnosed with type-2 diabetes / non insulin dependent diabetes, were enrolled. Metformin accounted with GI related problems and short duration of control of blood sugar levels when compared to Glibenclamide group.
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