Acta Biomedica Scientia

INCIDENCE OF DIFFERENT CLASS OF DRUGS USING IN ANAESTHETIC DEPARTMENT IN A SPECIALIZED CONSULTATIVE CARE HOSPITAL

Suryanarayana N & Mallik N.V.K

suresh00nallamalli@gmail.com

DDIs, adverse effects, interactions, antimicrobials, Anaesthetic

Introduction: For improvised patient care and safety monitoring hospitals should focus on the drug utilizations and pattern of medicine in all the departments of the hospital. Due to scarcity of studies on evaluation of drug interactions and indiscriminate drug use, there is need for planning and conducting more studies on the drug interactions and formulating public health policies. Use of more than one drug which is known as poly-pharmacy which represents administration of two or more drugs. Aims and Objectives: To assess the drug use pattern in patients of Anaesthetic department of a tertiary care hospital. To evaluate the incidence of drug-drug interactions. Materials and Methods: The study was carried out in 430 patients which was a prospective study designed to be carried out in a period of 3 months during the academic year of 2017- 2018, in the department of Anaesthetic in RVS Multi-Specialty Hospitals. Results and Discussion: It was assessed from the study that various class of drugs like Gastrointestinal drugs, CNS drugs, Antimicrobials, Drugs affecting blood and blood formation, Cardiovascular agents reportedly caused drug-drug interactions in patients admitted to Anaesthetic department. Number drugs and the types of drug involved in the interactions are clearly represented in the Table 1. Conclusion: It can be concluded from the study conducted in Anaesthetic department that antimicrobials are the major drugs class involved in Drug-Drug Interactions as observed. About 122 drugs are reported to involve in drug interactions with drugs affecting blood and blood formation and antimicrobials with major drugs in DDIs. Thus, regular monitoring of patient administered with drugs that act on blood and its formation and that acts as antimicrobials can help for prior evaluation of adverse effects eventually leading to decreased suffering of patient as well as economic burden.