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American Journal of Oral Medicine and Radiology

Volume 5, Issue 2, 2018
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
RELATIONSHIP OF SALIVARY LEVEL OF NITRIC OXIDE IN OBESE PATIENTS WITH CHRONIC PERIODONTITIS:A BIOCHEMICAL STUDY
Author
Kumar Vivek, Amrita, Singh Akanksha, Chandra Sourav
Email
drvivek1909@gmail.com
keyword
Nitric oxide, Obesity, Periodontitis, Saliva.
Abstract
Background: Nitric oxide (NO), a free radical gas, is a noxious chemical in the atmosphere acts as a physiological and pathophysiological mediator and it plays an important role in the biological systems. The levels of nitric oxide may provide intimation about the severity and the state of the underlying disease process. Hence, the aim of the present study was to assess the salivary levels of nitric oxide in obese patients with and without chronic periodontitis and non obese healthy patients. Methods: A total of 45 patients were divided into 3 groups. Group 1: Non‑obese healthy, Group 2: obese without chronic periodontitis and Group3: obese with chronic periodontitis. Whole saliva samples were collected, and NO levels were evaluated by using the griess method. The results were analyzed by SPSS and Mann–Whitney analysis. RESULTS: The highest nitric oxide levels from the Saliva were detected in group 3 while the lowest were detected in group 1. A significant difference in nitric oxide levels in the saliva was found when group 1 and group 2 was compared with group 3 (P<0.0001).Conclusion: The level of nitric oxide was higher in the saliva of chronic periodontitis patients. Nitric oxide may be used as an inflammatory marker for detection of periodontal disease.
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