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International Journal of Traditional System of Medicine

Volume 10, Issue 1, 2023
Mcmed International
International Journal of Traditional System of Medicine
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorijtsm@mcmed.us
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Abstract
Title
RECENT ALKALOIDS FROM DALBERGIA SISSOO AND VARIOUS HERBS AS ANTICANCER AGENTS
Author
GhogarePradip*, Chavan Vijay, Singh Priya, LambeSujata, HembadeMahendra, Lukkad Harish
Email
pradipghogare82@rediffmail.com
keyword
Antiproliferation, Antimetastasis, Berberine.
Abstract
Alkaloids are important chemical compounds that serve as a rich reservoir for drug discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and antimetastasis effects on various types of cancers both in vitro and in vivo. Alkaloids, such as camptothecin and vinblastine, have already been successfully developed into anticancer drugs. This paper focuses on the naturally derived alkaloids with prospective anticancer properties, such as berberine, evodiamine, matrine, piperine, sanguinarine, and tetrandrine, and summarizes the mechanisms of action of these compounds. Based on the information in the literature that is summarized in this paper, the use of alkaloids as anticancer agents is very promising, but more research and clinical trials are necessary before final recommendations on specific alkaloids can be made.
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