Acta Biomedica Scientia

STUDY OF ENDOMETRIAL PATHOLOGY IN THICKENED ENDOMETRIUM IN PERIMENOPAUSAL WOMEN WITH ABNORMAL UTERINE BLEEDING

*Sangeereni M., Mirunalini, S., and Mallika. A.

sangeereni@gmail.com

Abnormal uterine bleeding, histopathology perimenopausal, Ultrasonography.

Background: Abnormal uterine bleeding is a frequently encountered complaint in perimenopausal women(1,2) and also the most common cause of hysterectomy in this age group(3). Objective: The study of endometrial thickness by transvaginal USG with its histopathology correlation in abnormal uterine bleeding.Methods: A prospective study of 50 perimenopausal women with complaint of AUB with age group ranging from 40-51 years, those attending to the department of gynecology at. Rajah Muthiah Medical College and Hospital from 2015-2017. Clinical examination between parameters were analyzed. TVS study of endometrial pattern and thickness was done followed by dilatation of curettage (D&C). Histopathology examination report was correlated with ultrasonography.Results Out of 50 women, 62% belonged to the age group 40-45 years and 66% patients presented with menstrual complaints of menorrhagia which accounts for the common menstrual complaint 60% patient had endometrial thickness between 5.1-8mm.’most common type of endometrial pattern is proliferative endometrium. Sensitivity and specificity of TVS is 81.8% and 100%. Conclusion 1. Patient with AUB should be investigated promptly with transvaginal sonogram, as first line of investigation which is non invasive, safe and cost effective. 2. In perimenopausal age group when endometrial thickness is <8mm - it is correlated well with the histopathology report. In patients with endometrial thickness >8mm, a histopathological study of endometrium is warranted to rule out atypical changes or endometrial malignancy. 3. This study helps us to individualize treatment protocols between medical and surgical intervention.