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American Journal of Biological and Pharmaceutical Research

Volume 7, Issue 2, 2020
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
A PROSPECTIVE EVALUATION ON PRESCRIBING PATTERN AND OUTCOME OF ORAL HYPOGLYCEMICS AGENTS AMONG POST-MENOPAUSAL WOMEN
Author
S Thangamani, G S Sajini*, K Lovin , K Sajith , Kiran
Email
sgsajini@gmail.com
keyword
Diabetes mellitus, Postmenopausal women, Fixed dose combinations, Rational prescribing. Diabetes mellitus, Postmenopausal women, Fixed dose combinations, Rational prescribing. Diabetes mellitus, Postmenopausal women, Fixed dose combination
Abstract
Prescription trends in oral hypoglycemic agents keep on changing in post-menopausal women and thus the drug prescription study may prove to be powerful exploratory tool for health care providers. To study the prescribing pattern of oral hypoglycemics among postmenopausal women. A prospective observational drug utilization study was conducted in General Medicine OPD & IPD at Karuna Medical College Vilayodi, Chittur for a period of 6 months. The study is based on the data collected from 76 patients who were postmenopausal women visiting for the treatment of diabetes. A totally 76 prescriptions were analyzed and out of 44 (57.8%) were post-menopausal women having diabetes mellitus (DM) and both DM & hypertension (HT). A total of 451 drugs were prescribed, 252 (55.8%) were anti-diabetics and the remaining includes the others. Biguanides 80 (31.75%) most commonly prescribed, followed by sulfonylureas 65 (25.7%). Total 47 (18.6%) FDC’s were prescribed. After 2 weeks in Review 1 and Review 2 Metformin in monotherapy significantly reduced in FBS and RBS (FBS P≤0.05, RBS P≤0.0001) and in combination therapy Metformin with Glimepride significantly reduced FBS and RBS (FBS P≤0.05, RBS P≤0.0001) among post-menopausal women. Metformin is most commonly prescribed drug followed by glimepiride, voglibose and insulin preparations. In monotherapy, Metformin and sulfonylureas and in combination therapy metformin with glimepride prescribed patients were achieved their target among post-menopausal women with DM.
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