American Journal of Oral Medicine and Radiology

COMPARATIVE EVALUATION OF CLINICAL EFFICACY OF PROPOLIS AND TETRACYCLINE FIBRES AS LOCAL DRUG DELIVERY AGENTS IN TREATMENT OF PERIODONTITIS

Amera Ayubi , Nalini MS , Kavita Chandrasekaran

dr.ckavita@gmail.com

Propolis, local drug delivery, periodontitis.

Background: Propolis, sometimes called bee glue, is a natural resinous substance collected by honey bees. Various studies have confirmed its anti-inflammatory and anti-infective properties. Periodontitis is an inflammatory disease and in most of the cases advocates the use of an antimicrobial and anti-inflammatory agent to control the progression of the disease. Thus, this study was aimed at comparison of clinical evaluation of the efficacy of subgingivally delivered Indian propolis extract with tetracycline fibres in the treatment of periodontitis. Materials and methods: A total of 15 subjects (30 sites) were recruited for the study. The sites were randomly divided into two groups – group I and group II. The sites in group I received SRP followed by subgingival placement of tetracycline fibres and the sites in group II received SRP followed by subgingival placement of Indian Propolis as the local drug delivery agent. The clinical parameters of Gingival index (GI), plaque index (PI), probing pocket depth (PPD) and clinical attachment level (CAL) were recorded at baseline, 2 weeks and 3 months post drug delivery. Results: The results revealed that there is a significant reduction in the PI and GI in both the groups with slightly more reduction seen in group II (∆PI = 1.084±0.182; ∆GI = 1.7±0.116) compared to group I (∆PI = 1.09±0.249; ∆GI = 1.45±0.044). Also, the PPD and CAL showed significant improvement in both the groups with marginally better results in the group II (∆PPD = 2.634±0.268; ∆CAL = 1.754±0.032) compared to group I (∆PPD = 1.667±0.215; ∆CAL = 1.533±0.037). Conclusion: The results of the present study have shown that the Propolis is marginally better than tetracycline fibres as a local drug delivery agent in treating chronic periodontitis.