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Acta Biomedica Scientia

Volume 4, Issue 3, 2017
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
MOUTH DISSOLVING FILM: AN APPROACH TO NOVEL DRUG DELIVERY SYSTEM-A REVIEW
Author
Dhaneshwar Kumar Vishwakarma*, Angshu Banerjeer
Email
dhaneshwarvish@rediffmail.com
keyword
Fast Dissolving Oral Film, Oral Thin Films, Oral cavity.
Abstract
Mouth Dissolving Films (MDF) or Oral Thin Films (OTFs), offer a convenient way of dosing medications, not only to special inhabitants groups with swallowing difficulties such as Pediatrics and Geriatrics, but also to the general population. Fast dissolving drug delivery have been developed as an alternative to conventional dosage form as an oral means of drug delivery in case of chronic conditions. Present days fast dissolving films are preferred over conventional tablets and capsules for masking the taste of bitter drugs to increase the patient compliance. Mouth Dissolving Films consist of a very thin oral strip which dissolves in less than one minute when placed on the tongue. Dissolvable oral thin films are in the market since past few years in the form of breath strips and are widely accepted by consumers for delivering vitamins, vaccines and other drug products. Mouth Dissolving Films are the novel dosage forms that disintegrate and dissolve within the oral cavity. Intra-oral absorption permits rapid onset of action and helps by-pass first-pass effects, thereby reducing the unit dose required to produce desired therapeutic effect.
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