TELL : +91 0 99 08 87 07 06

 Mcmed International ®: Largest Journal Publication in world

International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
Recommend to
A Friend  | A librarian
Purchase
Purchase Issue
Abstract
Title
RARE SIDE EFFECTS OF PHENYTOIN: CASE REPORT
Author
Pradeep M. Venkategowda* , Naveen m nayak . Ashwini Murthy , Srividya .
Email
drpradeepmarur@gmail.com
keyword
Phenytoin, Seizures, Interstitial Nephritis, Bicytopenia, Lupus.
Abstract
Phenytoin is known for its antiseizure activity. It is used for management of tonic-clonic and partial seizures. Chronic treatment with phenytoin can be associated with side effects. This is a case report of 27 years old male who is a known case of seizure disorder since 3 months on phenytoin (300m/day) treatment, came to our hospital with history of fever, cough and generalized weakness for 3 days. Patient’s systemic examination was normal except for laboratory investigations which revealed anemia, thrombocytopenia, elevated serum creatinine and positive anti histone antibodies. Renal biopsy proved to be having acute interstitial nephritis. Diagnosed as phenytoin induced rare and multiple complications and hence phenytoin was stopped and managed with steroids, hemodialysis (short term) and other supportive medications. Patient condition improved significantly with normalization of serum creatinine levels. This case report highlights about rare side effects of phenytoin. Early diagnosis and management can reduce morbidity and mortality.
Download Broucher
Back to Top >>>>