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International Journal of Obstetrics and Gynaecology Nursing

Volume 10, Issue 1, 2023
Mcmed International
International Journal of Obstetrics and Gynaecology Nursing
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorijogn@mcmed.us
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Abstract
Title
A COMPARATIVE STUDY TO DETERMINE THE SAFETY AND EFFICACY OF INTRAVENOUS IRON SUCROSE AND INTRAMUSCULAR IRON SORBITOL THERAPY FOR IRON DEFICIENCY ANEMIA DURING PREGNANCY
Author
*Sujatha V, Radhiga C, Sudha R, Devika K, BuelaPriyadarshni, Shalini R
Email
sujathapunnami@gmail.com
keyword
Iron sucrose, Iron sorbitol, Pregnancy, Iron deficiency anemia.
Abstract
Aims and Objectives: To compare the safety, efficacy and rate of response of intravenous iron sucrose and intramuscular iron sorbitol therapy for anemia during pregnancy. Material and Methods:In this prospective study about 100 antenatal cases of gestational age 14–32 weeks were included. Cases were randomly divided into two groups. Group A, having 50 antenatal cases who received IV iron sucrose, and 50 antenatal cases in Group B who received IM iron sorbitol. Response to therapy in both groups were also studied and compared. Results: The mean hemoglobin (Hb) before therapy in group A was 6.49 g/dL and in group B was 6.47 g/dL. The increase in Hb after 4 weeks of starting therapy was 3.61 g/dL in group A and 2.36 g/dL in group B. The difference was statistically significant (P<0.01). The mean time taken to achieve target Hb (11 g/dL) was 6.42 weeks in group A and 9.09 weeks in group B. In group A, 10% (Five) cases had grade I adverse effects. In group B, 20% (10) cases had grade I adverse effects. The difference was statistically significant (P = 0.025). No case were discontinued the therapy in both the groups. Conclusion: IV iron sucrose is safe, convenient and also more effective, faster acting therapy than IM iron sorbitol therapy in treating moderate to severe anemia during pregnancy.
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