American Journal of Oral Medicine and Radiology

CURCUMIN: A NEOTERIC APPROACH FOR PERIODONTAL REGENERATION: A CASE REPORT

Krishna Kripal, Prathush Ajit Kumar*, Samba Siva Reddy, Sushma Reddy Bhavanam, Rekha BM, Kavita Chandrasekaran

ajithkumar.gunturu@gmail.com

Curcumin, Intra bony defects, Probing depth.

Introduction: Successful regeneration of the lost tissues is a major goal and challenge in periodontal therapy. The rationale behind the use of bone grafts or alloplastic materials is the assumption that both favor regrowth of alveolar bone and also the formation of new attachment would be stimulated. The recent approaches are directed towards a herbal bone graft material that is expected to regenerate bone with minimal complications. Turmeric has been used in Indian systems of medicine for a long time. The most active component of turmeric is curcumin, which makes up 2–5% of the spice. Curcumin (diferuloylmethane), the main yellow bioactive component of turmeric has been shown to have anti-inflammatory, antioxidant, antiallergic, anticarcinogenic, antimutagenic, anticoagulant, antifertility, antidiabetic, antibacterial, antifungal, antiprotozoal, antiviral, antifibrotic, antivenom, antiulcer, enhancer of healing, myogenesis, hypotensive, hypocholesteremic activities. Recent studies have shown that curcumin leads to significant reduction in bleeding on probing, probing pocket depth and gain in the clinical attachment level when used as a local drug delivery and subgingival irrigant. Further, curcumin has also demonstrated as a potential osteogenic material. Based on the above findings, we will discuss the characteristics of curcumin as well as report a few cases done in the department to evaluate the regenerative potential of curcumin in periodontal intra bony defects. Materials and Methods: A 34year old female patient reported to the Department of Periodontology, with a chief complaint of mobile tooth in relation to the distal aspect of 11 with grade II mobility in her upper front tooth region since 4 months. The oral hygiene status was fair. On intra oral examination, a periodontal pocket measuring 8mm in depth was found. Flap surgery was performed IRT 11,12 and curcumin gel was placed as a bone regenerative material and follow up done for 1,3, 6 and 9 months. Curcumin showed better results when used as a regenerative material and showed reduction in clinical variables namely probing pocket depth and clinical attachment level.