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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
ANTIMICROBIAL ACTIVITY OF PLANT EXTRACT OF CYCLEA PELTATA IN TOPICAL PREPARATIONS
Author
Sreelakshmi C*, Sreedevi G, Amal Fayas TS, Kavitha T
Email
sreelakshmi24jan@gmail.com
keyword
Cyclea peltata, Phytochemical, Antimicrobial, Disc diffusion, Ointment.
Abstract
The present study was under taken to evaluate in vitro antimicrobial activity of the successive leaf extracts of Cyclea peltata against various gram positive and gram negative bacterial strains using zone of inhibition. Disc diffusion method was used to evaluate the anti bacterial efficacy. The various strains were used for antibacterial examination such as E.coli, Staphylococcus aureus, Bacillus subtilis, Salmonella typhi. Aspergillus nigrum was used to evaluate the antifungal potential of the said plant extract. The reference antibiotics Gentamycin (antibacterial) and clotrimazole (antifungal) were also used to compare with that. The present research has been undertaken with the aim to evaluate the herbal ointment containing plant extract of Cyclea peltata have the antibacterial properties. Phytochemical screening of Cyclea peltata reveals the presence of alkaloids, glycosides, carbohydrates, saponins, tannins and phenol. The ointment was prepared by levigation method using ointment base. The physiochemical parameters of formulation such as pH, homogeneity and spreadability were determined. The Staphyllococcus aureus was more susceptible to the plant.
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