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Acta Biomedica Scientia

Volume 4, Issue 3, 2017
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
A COMPARATIVE STUDY OF SERUM HS-CRP LEVEL AMONG ISCHEMIC STROKE PATIENTS AND HEALTHY CONTROLS
Author
Ravindrapal , Anil Mangal , C.L Nawal
Email
20rps06@gmail.com
keyword
Stroke, Hypertension, CRP (C-Reactive Protein)
Abstract
Objectives to study, the high sensitivity C-reactive protein (hsCRP) level in Indian patients with ischemic stroke and to compare it with that of age and sex matched controls. Also, to evaluate the hsCRP level as a prognostic marker in cases of acute ischemic stroke. A case control study of 100 patients presenting with a history of focal neurological deficit of acute onset in the form of hemiparesis, hemianaesthesia, or having evidence of presence of ischemic infarct in CT scan of brain was done. In all patients hsCRP levels were measured within 72 hours of presentation. Most of the patients (65%) were in the age group of 50 -80 years. Left-sided hemiparesis with altered sensorium with facial palsy was the most common presenting symptom. hsCRP levels were found to be increased in stroke patients and on comparison with controls, the values were found to be significant (p < 0.001). Mean hsCRP level was 9.66 ±0.90 in non-survivors and 5.98 ± 1.79 in survivors of ischemic stroke. These values were found to be statistically significant (p < 0.001). From this study, we concluded that hsCRP level is increased in cases of ischemic stroke, suggesting an inflammatory response in acute stroke. Furthermore, the increased levels correlated with severe neurological deficit and worse outcome.
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