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International Journal of Advanced Paediatric Dentistry

Volume 4, Issue 1, 2019
Mcmed International
International Journal of Advanced Paediatric Dentistry
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorijapd@mcmed.us
Journal Home page
http://mcmed.us/journal/ijapd
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Abstract
Title
HIGH GRADE B CELL LYMPHOMA- A CASE REPORT
Author
Sahana N S, Roshni Sharma*, Srinath SK, Satish T Yadav, Pavana Gopinath
Email
drroshnisharma@gmail.com
keyword
B-cell lymphoma, hematolymphoid, keloid, Non-Hodgkin’s Lymphoma.
Abstract
Introduction: High grade B-cell lymphoma is a type of Non-Hodgkin’s Lymphoma which can involve lymph nodes and extranodal organs. The various types of non-Hodgkin's lymphoma are divided into high grade and low grade.Case report: An 8 year old male patient reported with complain of swelling and scar over right side of lower jaw. History revealed similar swelling 3 years back at the same site for which the patient underwent surgery through an extra-oral approach. Patient reported with an extraoral scar resembling a keloid and a diffuse swelling measuring 10cmX6cm extending from posterior border of ramus to submandibular region. Swelling was hard, fixed and tender on palpation. Incisional biopsy of the jaw lesion on routine histopathology showed large round cells with a centrally placed hyperchromatic nuclei resembling lymphocytes giving a picture of a hematolymphoid neoplasm. The tumor cells were positive for LCA, CD20 & PAX5, with a ki67 index >80% and BCL2 focally positive. No immunoreactivity noted for MPO, MyoD1, Tdt and synaptophysin.Conclusion: Based on histopathological and immunohistochemical findings, a final diagnosis of High grade B-cell lymphoma and extraoral keloid was given.
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