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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
DRESS: AN UNUSUAL CASE OF UPPER GASTROINTESTINAL BLEED
Author
Brian PH Chan and Khurram Khan*
Email
khankj@mcmaster.ca
keyword
DRESS, Drug Reaction, Gastrointestinal Bleed, CMV.
Abstract
A 77-year-old male was admitted to hospital following a four-week course of Piperacillin Tazobactam with drug reaction with eosinophilia and systemic symptoms (DRESS). During his admission, he had a severe upper gastrointestinal bleed (UGIB) and endoscopy revealed a large, circumferential ulcer at the incisura. DRESS is an adverse systemic reaction to a variety of medications, with a high mortality rate. Gastrointestinal bleed has previously been reported in association with DRESS, although this has only been in the setting of cytomegalovirus (CMV) reactivation. We report the first known case of severe UGIB in the setting of DRESS with negative CMV status.
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