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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
DISSEMINATED METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS OSTEOMYELITIS AND ENDOCARDITIS IN A PREMATURE INFANT
Author
Salma Sultana Syed
Email
syeds@ecu.edu
keyword
MRSA, Neonate, Osteomyelitis, Septic arthritis, Endocarditis.
Abstract
Although premature neonates are at increased risk for invasive infections, we questioned whether there were other documented cases of combined osteomyelitis, septic arthritis, and infective endocarditis (IE) due to Methicillin-resistant Staphylococcus aureus (MRSA) and whether adequate modalities of diagnosing osteomyelitis in neonates exist. Such severe complications of disseminated infection are rarely described in the literature before two weeks of life. To our knowledge this is the first case of disseminated MRSA with all three complications of bone and joint infections and IE described in a premature neonate. Unlike most neonates described, this patient’s presentation is consistent with typical presentations of osteomyelitis in older children. This case demonstrates that dissemination of MRSA in neonates may involve multiple sites simultaneously. It also reminds us that bone and joint infections in infants have varied presentations, in this case similar to that seen in older children and adults. More studies are needed to study the varied presentations and diagnosis of disseminated MRSA infections in infants to prevent significant morbidity and mortality.
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