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European journal of molecular biology and biochemistry

Volume 6, Issue 1, 2019
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
A STUDY ON MEASUREMENT OF SERUM AND PLEURAL FLUID TOTAL PROTEIN, ALBUMIN, LDH AND PROTEIN THIOLS IN PATIENT WITH PLEURAL EFFUSION
Author
Moin Sabeer*
Email
drmoinsabeer@yahoo.com
keyword
Total Protein, Albumin, LDH, Pleural Effusion.
Abstract
For the past several decades, transudates have been differentiated from exudates, according to Light’s criteria, by measurement of levels of protein and LDH in the serum and the pleural fluid. But the problem of “pseudoexudate’, that is elevated protein content of an effusion with diuretic use in patients of congestive heart failure later confirmed by Romero et al leads to the proposal of serum effusion albumin gradient. A total of 56 patients of pleural effusion were taken with diverse etiology, then venous blood sample and pleural fluid were collected from these patients after diagnosing clinically, radiologically and after thoracocentesis. The study included 56 clinically diagnosed patients with pleural effusion of diverse etiology, who were divided into 2 groups based on etiology and clinical diagnosis .Group I (exudates): comprising 30 cases of tuberculous (n=21), malignant (n=7), Empyema (n=2) and Group II (transudates): Comprising 26 patients of congestive heart failure (n=l4) anemia (n=5), and Cirrhosis (n=7).
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