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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
PAEDIATRIC NASOPHARYNGEAL CARCINOMA: A RARE CASE REPORT AND REVIEW OF LITERATURE
Author
Anil Pandey*, Deepak Verma, Uma Garg, Naveen Sharma, Parveen Rana Kundu, Ruchi Agarwal, Vikas Dhillon
Email
anilpandeys@gmail.com
keyword
Epstein Barr Virus, Nasopharyngeal carcinoma, Radiotherapy.
Abstract
2016 Revised 27/09/2016 Accepted 12/10/2016 Key words: Epstein Barr Virus, Nasopharyngeal carcinoma, Radiotherapy. ABSTRACT Nasopharyngeal carcinoma (NPC) is a rare malignancy and is one of the commonly misdiagnosed and poorly understood disease. It accounts for 1-5% of paediatric cancers and predominantly seen in adolescent male. Despite multi-factorial pathogenesis, strong association with Epstein Barr Virus has been found in genetically susceptible host. In younger patients more aggressive biological behaviour has been observed, although overall survival is better as compared to adults. As the condition is rare and clinical presentation is non-specific, diagnosis is often delayed and misinterpreted in paediatric patients. EBV-DNA levels are used to monitor the disease in these patients and also have a prognostic values also. Radiotherapy has been used as the main stay of treatment for early disease while concurrent chemo-radiotherapy has been demonstrated to prolong survival in loco-regionally advanced disease. There is paucity of data in Indian paediatric patients. We are presenting such case for its rarity.
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