TELL : +91 0 99 08 87 07 06

 Mcmed International ®: Largest Journal Publication in world

American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
Recommend to
A Friend  | A librarian
Purchase
Purchase Issue
Abstract
Title
DETERMINATION OF ANTIBACTERIAL ACTIVITY OF NIGELLA SATIVA SEED EXTRACT AGAINST SOME HUMAN PATHOGENIC BACTERIA
Author
Wasim Raja1 and Tikeshwar Dewangan1, 2
Email
drwasimraja84@gmail.com
keyword
Antimicrobial activity; disk diffusion method; methanol extract; Nigella sativa; pathogenic bacteria
Abstract
Nigella Sativa (NS) seeds have been used for medicinal purposes for centuries both as herbs and its seed oil. In Islam it is regarded as one of the greatest forms of healing medicine included in the medicine of Prophet Mohammed (SAW). Pathogenic bacterial infections have become a major health problem worldwide. New antimicrobial agents are urgently needed to overcome this problem. In this study, antibacterial activity of Nigella sativa seed extract against some pathogenic bacterial strains gram negative bacteria; Acetobactor, Citrobactor and E. coli and gram positive bacteria; Bacillus subtilis, S. aureus and Enterobacter was evaluated. This study show that methanolic fruits extract of Nigella sativa Linn inhibits the growth of micro organism dose dependently. A significant correlation was observed between zone of inhibition and concentration of extract. These results confirm the antibacterial activity of Nigella sativa seed and support the traditional use of the plant in therapy of bacterial infection. These promising findings suggest the presence of antibacterial activity in the tested plant material, exhibited by its bioactive compounds, and serving them as an alternative antimicrobial agent.
Download Broucher
Back to Top >>>>