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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
BLOOD SUBSTITUENTS AN OVERVIEW
Author
D. Likhitha, M. Shankar*, S. Kavya Lalitha, T. Supriya, M. Niranjan Babu
Email
shankarmanichellappa2014@gmail.com
keyword
Human hemoglobin, Photodynamic, Biochemical technology.
Abstract
Blood is a special type of connective tissue that is composed of white cells, red cells, platelets and plasma. A blood substitute is a substance used to mimic and fulfill some functions of biological blood. It aims to provide an alternative to blood transfusion, which is transferring blood or blood based products from one person into another. Artificial blood is a product made to act as a substitute for red blood cells. The main categories of oxygen carrying blood substitutes being hemoglobin based oxygen carriers and perfluoro carbon based oxygen carriers. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. To obtain hemoglobin, a strain of E. coli bacteria that has the ability to produce human hemoglobin is used. Synthetic oxygen carriers may also show potential for cancer treatment, as their reduced size allows them to diffuse more effectively through poorly vasculated tumour tissue, increasing the effectiveness of treatments like photodynamic therapy and chemotherapy.
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