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Acta Biomedica Scientia

Volume 4, Issue 3, 2017
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
ANTIMICROBIAL RESISTANCE IN E. COLI AT BENUE STATE UNIVERSITY TEACHING HOSPITAL (BSUTH), MAKURDI, NIGERIA
Author
Jombo GTA1*, Ojo BO2, Abba PO3
Email
jombogodwin@yahoo.com
keyword
Antibacterial, Escherichia coli, Resistance
Abstract
The study reports three cases of extreme high rates of antimicrobial resistance of Escherichia coli isolates by the Microbiology laboratory within three weeks. This is based on findings from antimicrobial susceptibility reports on Escherichia coli of patients during routine laboratory procedures on submitted clinical samples in the first three weeks of March, 2014. Specimens were collected, transported, stored and processed using standard laboratory procedures, and susceptibility tests were carried out using modified Kirby-Bauer’s method. Among the 11 antibiotics that are routinely tested for activity against E.coli, all the three isolates were resistant to amoxicillin, amoxicillin-clavulanic acid (augmentin), perfloxacin, cotrimoxazole. gentamicin, ciprofloxacin, ofloxacin, ceftriaxone, chloramphenicol, and cefuroxime but all were susceptible to Streptomycin. Empirical treatment of E. coli infections with third generation cephalosporins and quinolones should be carried out in line with the local sensitivity patterns of such drugs in order to avoid therapeutic failure with them.
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