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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
EVALUATION OF ENDOGENOUS ANTIOXIDANT STATUS OF PREGNANT DOG
Author
Sudesh Agarwal, Satyendra, B.S.Saini, Mamta Saini, S.S.Singhal, Ashish Joshi and Nalini Kataria
Email
nalinikataria@rediffmail.com
keyword
Antioxidants, German Shepherd, oxidative stress, pregnant.
Abstract
The present investigation was carried out to evaluate endogenous antioxidant status of pregnant dogs. Sera were obtained to determine endogenous antioxidants like vitamin A, C, E and glutathione in healthy pregnant and non pregnant adult female German Shepherd dogs. Results exhibited significant (pï‚£0.05) decrease in the values of serum vitamin A, C, E and glutathione during pregnancy as compared to non pregnant state. It indicated depletion of antioxidant status of pregnant dogs. It signified the development of oxidative stress in pregnant dogs. Greatest percent change was observed in the mean value of serum glutathione. The present investigation has tried to evaluate the relationship of antioxidants with the oxidative stress. It can be concluded that pregnancy produced the oxidative stress in the dogs. Interpretation of these variations will help to provide perceptive approach of various hidden mechanisms in the development of oxidative stress. Results undoubtedly demonstrated that apart from diseases, other stressors can also be a factor in the development of oxidative stress and pregnancy is one of them. Canines must be supplemented with antioxidants to enhance endogenous antioxidant status to safeguard them from the danger of oxidative stress throughout pregnancy.
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