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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
ASSESSMENT OF SERUM RETINOL LEVEL AND ITS CLINICAL ASSOCIATION IN CHILDREN
Author
K. Srinivasa Rao1, K. Kalyan Kumar2, Usha L H3
Email
srini.nmc@gmail.com
keyword
serum vitamin A; malnutrition; albumin; anemia; retinol
Abstract
Present study was aimed to determine the serum retinol levels in malnourished children in the age group 1 – 10yrs and to determine the relationship between the serum retinol level and clinical presentation. To compare serum retinol level in age and sex matched malnourished and apparently normal children. The study group comprised of 50 cases and 50 controls of ages between 1-10yrs. Informed consent was obtained from each child. The study was approved by ethical committee, Navodaya Medical College Hospital and Research Centre, Raichur. The nutrition was assessed according to IAP classification for children under the age of 5yrs and according to WHO classification for children between 6-10yrs. The blood sample was taken from the subjects and serum retinol level was estimated according to modified Carr Price reaction. And the level was noted. The cases were compared with age and sex matched controls. Statistical analysis was done using the software SSPS. Results of the present study show that, malnourished children have low serum retinol levels. Children consuming vitamin A poor diet had low serum retinol level. The serum retinol is more reduced in children with recurrent infections, or / and who have suffered measles in past 1-3months. In malnourished children the serum albumin in reduced and children with reduced serum albumin have low serum retinol levels. Children with moderate to severe anemia have low serum retinol levels.
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