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American Journal of Oral Medicine and Radiology

Volume 5, Issue 2, 2018
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
GRADING OF GLIOMAS ON THE BASIS OF MR PERFUSION DIFFUSION AND SPECTROSCOPY
Author
Ambresh RD* and Prakash Jain RB
Email
drambresh1@rediffmail.com
keyword
Glioblastoma multiforme, rCBV (relative cerebral blood volume) ADC (apparent diffusion co-efficient) astrocytoma.
Abstract
Intracranial tumors are a significant health problem. Tumors related to central nervous system (CNS) are 1-2% of all malignancies1.among which gliomas forms 70-80% of primary tumours. Magnetic resonance (MR) is the imaging modality of choice to evaluate intracranial tumors, and it continues to have an ever expanding with its newer techniques our study is to establish a relation between rCBV(relative cerebral blood volume) and ADC(apparent diffusion co-efficient) with tumor grade for gliomas. To estimate a cutoff rCBV and ADC value for differentiation of high and low-grade gliomas, and to access the diagnostic accuracy of MR spectroscopy in grading of gliomas. A total of at least 30 patients of glioma included in the study Basic MRI sequences, perfusion, diffusion and spectroscopy done The ADC values, rCBV values obtained for different tumor grades were analyzed statistically using stata software version 11.2. RESULTS: Low grade (I + II) gliomas shows ADC values >0.804 x 10-3mm2/sec, Grade III gliomas show ADC values 0.677-0.804x10-3mm2/sec while Grade IV gliomas shows ADC values <0.677x10-3mm2/sec Low grade (I + II) gliomas show rCBV values <2.5ml/100mg. Grade III show rCBV values 2.5-3.3ml/100mg while Grade IV gliomas show rCBV values >3.3ml/100mg.
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