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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
ANTIOXIDANT ACTIVITY OF ISOLATED COMPUNDS IN COCHLOSPERUM VITIFOLIUM
Author
G. Sandhyarani1*, K.Swathi2, Gangarapu.Kiran3, K. Praveen Kumar4, Alli Ramesh4
Email
sandhyaguggilla9@gmail.com
keyword
Cochlosperum vitifolium; free radicals
Abstract
The antioxidant properties of four successive extracts of Cochlosperum vitifolium and the successive chloroform extract fraction, CV-11, were tested using standard in vitro model. The amount of the total phenolic and flavonoid content was also determined. The successive chloroform extract, CVC and its fraction CVCF -28 exhibited strong scavenging effect on 2,2-diphenyl-2-picryl hydrazyl (DPPH), Nitric oxide, 2,2 -azino-bis (3ethylbenzo-thiazoline-6-sulphonic acid) diammonium salt (ABTS) radical cation, Reducing power, p-NDA and hydrogen peroxide methods. The free radical scavenging effect of CVC and CV-11 was comparable with that of reference antioxidants. These results clearly indicate the strong antioxidant property of the plant Cochlosperum vitifolium. The study provides a proof for the ethnomedical claims and reported biological activities. The plant has, therefore, very good therapeutic potential.
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