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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
PANDRUG- RESISTANT KLEBSIELLA SPECIE: CASE REPORT OF AN UNUSUAL ANTIMICROBIAL SUSCEPTIBILITY PATTERN
Author
Jombo GTA*, Mbaave PT, Abba PO
Email
jombogodwin@yahoo.com
keyword
Antimicrobial Susceptibility, Klebsiella, Resistance.
Abstract
Klebsiella species over the past decade have continued to pose difficulties in its treatment with antibiotics due to its high resistance across the globe. This study was based on observation of resistance pattern of the bacterium in a new university teaching hospital in West Africa.This study was carried out to ascertain the scope of antimicrobial resistance of a Klebsiella specie from urine sample of a patient. Urine sample from a male patient was collected into sterile universal bottle, transported to the laboratory and processed using standard laboratory methods. These include macroscopy, wet preparation, Gram stain, inoculation to culture media and incubation, and biochemical tests where Klebsiella was identified. Antibacterial susceptibility test was carried out on Mueller-Hinton agar using modified Kirby-Bauer disk diffusion method and results interpreted as either resistant or sensitive. The Klebsiella spp was resistant to Ampicillin, Ciprofloxacin, Erythromycin, Streptomycin, Cefuroxime, Gentamycin, Ceftriaxone, Perfloxacin, Tetracycline, Amoxycillin, Clavulanate+Amoxicillin (Amoxiclav) and Co-trimoxazole but sensitive to only clindamycin. Empirical treatment of infections with antibiotics should generally be scaled down in the tropics and sale and intake of antibiotics at community level properly controlled and legislated. Also the option of introducing automated and semi automated techniques with advantage of shortened time in sensitivity testing be explored for rather definitive treatment of infections.
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