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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
HIRSCHPRUNG’S DISEASE- A REVIEW ARTICLE
Author
Neha Laxmichand Shah* and Pragati Salil Upasham
Email
nehshah_culdoc@yahoo.com
keyword
Agangliosis, Auerbach plexus, Meissner plexus, rectal suction biopsy, Acetylcholinesterase and Calretinin.
Abstract
Hirschprung’s disease is a congenital disorder characterized by the absence of myenteric and meissner plexuses in the distal colon. It should be considered in a new born who has failed to pass mechonium within 24-48 hours.Accurate diagnosis is a key element for further treatment. Rectal suction biopsy along with H & E staining and acetylcholinesterase and calretenin histochemistry offers a high diagnostic accuracy.
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