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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
EVALUATION OF ANTHELMINTIC ACTIVITY OF ETHANOLIC EXTRACT OF ANTIGONON LEPTOPUS
Author
Poonam Ranjan*, Sushil Pratap, Dilip Kumar Tiwari, Kishu Tripathi
Email
kishutripathi@rediffmail.com
keyword
Antigonon leptopus leaves, Albino rat, Indian earthworm, Leech, Anthelmintic activity, Ethanolic extract.
Abstract
To evaluate the anthelmintic activity of ethanolic extract of leaves of Antigonon leptopus. The activity was carried out on adult Indian earthworm (Pheretima posthuma) and leech (Hirudo medicinalis). In this study, 20 mg/ml, 40 mg/ml, 60mg/ml, 80mg/ml, 100mg/ml, 120mg/ml and 140mg/ml concentrations of plant extract were tested which involved the time of paralysis and time of death. Piperazine citrate (10mg/ml) was taken as a reference standard drug whereas distilled water was referred as a vehicle. The extract exhibited significant anthelmintic activity which was more in higher concentration extract. So it was concluded from the present study that the plant of Antigonon leptopus exhibited significant anthelmintic activity.
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