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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
CORRELATION OF FSH, LH AND PROLACTIN WITH INFERTILITY IN REPRODUCTIVE AGE GROUP WOMEN
Author
Santosh Fupare*, Rajesh K. Jambhulkar, Archana Tale
Email
drsantoshfupare@rediffmail.com
keyword
Infertility, FSH, LH, Prolactin, Chemiluminescence, etc.
Abstract
The infertility problem is more common phenomenon among the women now days and has increased over past 30 years. The present study was carried out to correlate FSH, LH and prolactin with infertility in the reproductive age group of women. The aim of this research work was to correlate FSH, LH and prolactin with infertility in the reproductive age group of women. Total 120 infertile women, and 80 normal fertile women volunteers were selected on OPD basis between age group of 19 to 45 years. Out of 120 infertile women, 80 were of primary infertility and 40 of secondary infertility. They were screened for FSH, LH and prolactin status by Chemiluminescence Immunoassay (CLIA). Prolactin is significantly high in primary infertility as compared to secondary infertility. LH and FSH values were low in infertile as compared to fertile, but among primary and secondary infertility their values not differ. Hyperprolactinemia may result in menstrual disorders. Oligomenorrhoea was most common in infertile women. Hyperprolactinemia patients exhibit ovulatory failure. Hence, assessment of serum prolactin levels is mandatory in the work up of all infertile women, especially those presenting with menstrual irregularities. So the basic approach should be to identify those individuals who have hyperprolactinemia because they are at greatest risk for the development of infertility. So FSH, LH and Prolactin screening of all females of early reproductive age group should be done so as to detect subclinical hormonal problem and to prevent infertility risk.
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