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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
ORGNOPHOSPHATE POISONING AND ITS NEUROLOGICAL MANIFESTATIONS
Author
Pradeep M Venkategowda, Yogesh R Harde, Manimala Rao, Dnyaneshwar P Mutkule Surya P Yarramalle, Mithilesh K Raut
Email
manimalarao@hotmail.com
keyword
Poisoning, Organophosphate, Cholinergic crisis, Intermediate syndrome, Neuropathy.
Abstract
Organophosphate (OP) compounds are one of the common cause poison related hospital admission in India with varying morbidity and mortality. These poisons cause various clinical manifestations due to inactivation of acetylcholine esterase enzyme at muscarinic, nicotinic and central nervous system. Multiple types of neurological disorders are associated with OP compound poisoning, such as Acute cholinergic crisis, Intermediate syndrome (IS), Organophosphate induced delayed polyneuropathy (OPIDN), Chronic organophosphate induced neuropsychiatric disorder (COPIND) and very rarely Guillain-Barre syndrome (GBS). Early diagnosis and management can reduce morbidity and mortality.
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