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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
ANALGESIC ACTIVITY OF METHANOLIC EXTRACT OF GRACILARIA CORTICATA J.AG. (RED SEAWEED) IN HARE ISLAND, THOOTHUKUDI, TAMIL NADU, INDIA
Author
Iniya Udhaya C and John Peter Paul J*
Email
johnarock2008@yahoo.com
keyword
Analgesic, Seaweeds, Gracilaria, Hare island.
Abstract
The present study was carried out to determine the analgesic activity of methanolic extract of Gracilaria corticata J.Ag. in Hare island, Thoothukudi, Tamil Nadu, India. The dried powdered Gracilaria corticata J.Ag. was extracted in absolute methanol to estimate the analgesic activity. The analgesic activity was assessed on intact mice by tail flick latency in tail immersion method. Diclofenac Sodium in the dose of 100mg/kg was used as standard drug. Methanolic extracts of Gracilaria corticata J.Ag. were given in the doses of 200 and 400mg/kg. Control group received normal saline solution. All the doses administered orally. Results showed that both the doses of methanolic extracts of Gracilaria corticata J.Ag. had potent analgesic activity. From the observations, it was concluded that methanolic extract of Gracilaria corticata J.Ag. at 200mg/kg was found to have more effect compared to 400mg/kg methanolic extract.
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