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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS ASSOCIATED WITH DESMOPLASTIC SMALL ROUND CELL TUMOR
Author
Valentina G. Dell’Orto V and Brazzola PL*
Email
pierluigi.brazzola@eoc.ch
keyword
Hemophagocytic Lymphohistiocytosis (HLH), Desmoplastic small round cell tumor (DRCST), Cryptococcus neoformans.
Abstract
We report on the case of an 18-year-old young woman affected by a desmoplastic small round cell tumor (DRCST) treated with chemotherapy (P6 protocol), surgery and adjuvant radiotherapy. During maintenance therapy, she experienced fever and pancytopenia. Laboratory tests showed: hyperferritinemia, hypertriglyceridemia, high levels of soluble IL-2 receptor (sIL-2r) and in the bone marrow aspirate, an evident hemophagocytosis. Therefore, she was treated for hemophagocytic lymphohistiocytosis (HLH), but she died during therapy.
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