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American Journal of Advanced Medical & Surgical Research

Volume 2, Issue 1, 2016
Mcmed International
American Journal of Advanced Medical & Surgical Research
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorajamsr@mcmed.us
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Abstract
Title
RISK FACTORS THAT ARE ASSOCIATED WITH DEVELOPMENT AND SEVERITY OF LARGE FIBER POLYNEUROPATHY IN TYPE 2 DIABETICS IN SAUDI POPULATION: A RETROSPECTIVE CASE CONTROL STUDY
Author
Aysha Al Shareef*
Email
kdraysha@hotmail.com
keyword
Diabetes, Polyneuropathy, Risk factors, Severity of polyneuropathy.
Abstract
Diabetic large fiber polyneuropathy (DLPN) is a well known complication of type 2 diabetes. Other than glycemic control there is no definitive treatment available for effective treatment of DLPN. Thus identifying the risk factors for development and their association with severity of DLPN in diabetic patients helps to understand and treat the DLPN effectively. To study the effect of different variables, development and severity of DLPN as compared to controls. A retrospective case control study conducted in a university hospital in the western region of Saudi Arabia. The sample of cases was collected retrospectively from year 2005 – 2012. A total of 122 patients with established diagnosis of diabetes were subjected to Electromyography (EMG) and nerve conduction Studies (NCS) to identify the patients who had DLPN and to see whether statistical significance with the various possible risk factor in development and severity of DLPN In case and control groups. The study showed no statistical correlation between the potential predictors studied and the development and severity of DLPN in study group, diabetic patient with DLPN and controls. In Saudi type 2 diabetic population studied there was no correlation between the various predictors’ development and severity of DLPN. Larger prospective studies may be needed to identify the potential risk factors for the development of DLPN.
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